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| Review: Tuberculin Skin Testing in Patients with HIV Infection: Limited Benefit of Reduced Cutoff Values | |
Attached file: |
(Russian, 273.6 kb)
Review: Tuberculin Skin Testing in Patients with HIV Infection: Limited Benefit of Reduced Cutoff Values
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Link to document(s) | http://www.ncbi.nlm.nih.gov... |
Author(s): | Cobelens F. et. al |
Document type: | Literature Reviews |
Language: | English, Russian |
Original language of document: | Russian |
Primary area(s) of focus: | HIV/AIDS |
Secondary areas of focus: | Tuberculosis |
Submited by: | Victor Stanilevskiy |
Material written specifically for patients: | No |
Date of entry: | September 13, 2006 |
Pages: | 3 |
| When determining eligibility for isoniazid preventive therapy of human immunodeficiency virus (HIV)-infected patients, the cutoff value of the tuberculin skin test (TST) is often reduced from an induration of 10 mm in diameter to one of 5 mm in diameter to compensate for loss of sensitivity. The effectiveness of this reduction depends on the underlying mechanism: a gradual decrease in skin test responsiveness with decreasing immunocompetence or an all-or-nothing switch to complete anergy. No published studies have assessed this directly in patients with tuberculosis. | |
Overall user rating: | Not yet reviewed |
